New radiation approach aims to stop pancreatic cancer return after surgery

NCT ID NCT05043857

Ongoing Disease control Sponsor: Istituto Clinico Humanitas Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This phase 2 trial tests whether a precise, high-dose radiation technique called SBRT can lower the chance of cancer coming back in the pancreas area after surgery. The study involves 50 adults with pancreatic cancer who had surgery and are at high risk of recurrence. They will receive SBRT in 5 sessions, targeting the surgical bed and nearby areas.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Stereotactic Body Radiotherapy (SBRT)
What this could lead to: If successful, this could offer a more effective and shorter radiation option after surgery to help prevent the cancer from coming back in the pancreas area.
What could go wrong: This is a small, early-phase trial (50 people) without a comparison group, so results may not be definitive. Radiation can also cause side effects to nearby organs.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

malignant pancreatic neoplasm pancreatic adenocarcinoma pancreatic neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

PANCREAS CANCER

Contacts and locations

Locations

Humanitas Research Hospital

Rozzano, MI, 20089, Italy

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