Heart shield after pregnancy: statin trial targets lasting damage

NCT ID NCT06632379

Recruiting now Disease control Sponsor: Ohio State University Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether taking atorvastatin (a statin) for 3 months after childbirth can reduce the long-term risk of heart disease in women who had high blood pressure disorders during pregnancy. 76 postpartum women will receive either atorvastatin or a placebo, and their cardiovascular risk scores will be measured. The goal is to see if this short-term treatment can improve heart health years later.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: atorvastatin
What this could lead to: If it works, this could point toward a simple way to reduce long-term heart disease risk in women who had high blood pressure during pregnancy.
What could go wrong: This is a small, early-phase trial with only 76 participants, so results may not apply to everyone. The drug is taken for just 3 months, and side effects are possible.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

hypertension, pregnancy-induced hypertensive disorder preeclampsia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

GESTATIONAL HYPERTENSION HYPERTENSIVE DISORDERS OF PREGNANCY PREECLAMPSIA

Contacts and locations

Locations

The Ohio State University Wexner Medical Center OB/GYN Maternal and Fetal Medicine
RECRUITING

Columbus, Ohio, 43210, United States

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