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Massive UK study tracks 12,000 women and their children for 20 years to unlock secrets of lifelong health

NCT ID NCT04715945

Knowledge-focused Sponsor: University of Southampton Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing This study
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This long-term study recruited over 12,000 non-pregnant women in Southampton, UK, and followed about 3,000 of them through pregnancy and their children's growth up to age 19. Researchers are tracking body composition, nutrition, asthma, and heart health to understand how a mother's health before and during pregnancy influences her child's development. The goal is to identify early-life factors that could prevent obesity, asthma, and other health problems later in life.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this study could reveal key factors before and during pregnancy that shape a child's long-term health, pointing to ways to prevent obesity, asthma, and other conditions.
What could go wrong
This is an observational study, not a treatment trial. It can show links but not prove cause and effect. Results may take years to influence medical practice.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

12,583 people

The number who actually took part.

Started

Apr 1998

Expected to finish

Dec 2028

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

All non-pregnant women in the correct age group living in Southampton between 1998 and 2002 were eligible.

Ages

20 to 34 years

Sex

Female participants only

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Not pregnant, resident in Southampton UK. Exclusion Criteria: * GP requested no contact

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Conditions

The condition(s) this trial relates to.

Bone Diseases, Metabolic Child Behavior childhood onset asthma Nutritional and Metabolic Diseases osteoporosis Pediatric Obesity

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Asthma in children Bone loss Cardiovascular risk factor Child behavior Child development Child obesity Nutritional and metabolic diseases

More trials for these conditions

Other studies related to the condition(s) this trial covers.