Twin study seeks genetic clues to childhood brain cancer
NCT ID NCT06054295
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This pilot study is looking at 25 pairs of identical twins where only one twin has a childhood brain tumor. Researchers will collect blood and saliva samples to search for small genetic differences, called somatic mosaicism, that might explain why one twin got sick and the other stayed healthy. The goal is to better understand what causes these tumors, not to test a new treatment.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
What this could lead to
If successful, this study could help explain why some children develop brain tumors while their identical twin does not, pointing toward new ways to understand or predict cancer risk.
What could go wrong
This is a very small pilot study with only 50 participants, so findings may not apply to all children. It is designed to gather information, not to test a treatment, so there is no direct benefit to participants.
Disclaimer
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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University of Minnesota
RECRUITINGMinneapolis, Minnesota, 55455, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••