New study: can a simple powder keep kidney patients out of the ER?
NCT ID NCT05347693
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study looked at whether continuing a drug called sodium zirconium cyclosilicate (Lokelma) after hospital discharge helps people with chronic kidney disease maintain normal potassium levels. 186 hospitalized patients were randomly assigned to either continue the drug or receive standard care. The goal was to see if the drug reduces potassium-related hospital visits and keeps potassium in a healthy range for 180 days after discharge.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- sodium zirconium cyclosilicate (Lokelma)
- What this could lead to
- If it works, this could show that continuing this medication after leaving the hospital helps keep potassium levels normal and reduces the need for emergency care.
- What could go wrong
- This is a completed phase 4 study with 186 participants, so results are available but may not apply to all patients. The open-label design means both patients and doctors knew which treatment was given, which can bias results.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Research Site
Bonheiden, 2820, Belgium
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Leuven, 3000, Belgium
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Annonay, 07103, France
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Ars-Laquenexy, 57530, France
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Nice, 06000, France
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Saint-Priest-en-Jarez, 42270, France
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Bari, 70120, Italy
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Foggia, 71122, Italy
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Parma, 43125, Italy
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Pavia, 27100, Italy
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Eindhoven, 5602 ZA, Netherlands
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Algeciras, 11207, Spain
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Almería, 04009, Spain
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Badajoz, 06080, Spain
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Barcelona, 08907, Spain
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Burgos, 9006, Spain
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Getafe, 28905, Spain
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Madrid, 28007, Spain
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Madrid, 28040, Spain
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Salamanca, 37007, Spain
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San Sebastián de los Reyes, 28702, Spain
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Seville, 41009, Spain
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Talavera de la Reina, 45600, Spain
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Zamora, 49022, Spain
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Doncaster, DN2 5LT, United Kingdom
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Research Site
Hull, HU10 7AZ, United Kingdom
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Salford, M6 8HD, United Kingdom
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Research Site
Stevenage, SG1 4AB, United Kingdom
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