Can a sleep drug help people with PSP rest better?

NCT ID NCT04014387

First seen Nov 01, 2025 · Last updated May 15, 2026 · Updated 28 times

Summary

This study tested two sleep medications (suvorexant and zolpidem) against a placebo in 40 adults with progressive supranuclear palsy (PSP), a brain disease that disrupts sleep. Each person tried all three options for one week each, with a week off in between. The goal was to see if targeting wake-promoting brain areas could improve sleep quality and daytime well-being.

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Contacts and locations

Locations

  • University of California- San Francisco

    San Francisco, California, 94158, United States

Conditions

Explore the condition pages connected to this study.