Brain scans to unravel why poor sleep worsens back pain

NCT ID NCT06973837

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looks at how chronic sleep problems and pain sensitivity are connected in people with long-term low back pain and insomnia. Researchers will use brain imaging, pain tests, and blood/stool samples in 80 adults to understand the underlying brain mechanisms. The goal is to gather knowledge, not to test a treatment.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to
If successful, this could reveal brain mechanisms linking sleep and pain, pointing toward better treatments for chronic back pain and insomnia.
What could go wrong
This is an observational study, not testing a treatment. It is small (80 people) and early-stage, so findings may not apply broadly or lead directly to new therapies.

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Conditions

The condition(s) this trial relates to.

Chronic Pain insomnia Neuroinflammatory Diseases neuronitis Pain

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • UZ/KU Leuven

    RECRUITING

    Leuven, 3000, Belgium

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