New antibody aims to quiet seizures
NCT ID NCT07051629
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This early-stage trial tests a new drug called SIF001, a monoclonal antibody designed to treat epilepsy. Researchers are giving the drug to healthy volunteers and people with epilepsy to check its safety, how the body processes it, and what side effects may occur. The study uses a placebo for comparison and gradually increases the dose to find the safest range.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- SIF001 (a monoclonal antibody)
- What this could lead to
- If safe and effective, SIF001 could offer a new way to control seizures in people with epilepsy.
- What could go wrong
- This is an early Phase 1 trial focused on safety, not yet on effectiveness. The drug may not work or could have side effects.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Accel Research sites network
RECRUITINGDeLand, Florida, 32720, United States
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Center for Neurosciences
RECRUITINGTucson, Arizona, 85718, United States
Contact Email: •••••@•••••
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D&H Tamarac Research Center, LLC
RECRUITINGTamarac, Florida, 33321, United States
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Dent Neurologic Institute
RECRUITINGAmherst, New York, 14226, United States
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Encore Medical Research of Weston, LLC
RECRUITINGWeston, Florida, 33331, United States
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Hawaii Pacific Neuroscience, Comprehensive Epilepsy Center
RECRUITINGHonolulu, Hawaii, 96817, United States
Contact Email: •••••@•••••
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Horizon Clinical Research Center
RECRUITINGCypress, Texas, 77429, United States
Contact Email: •••••@•••••
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Mid-Atlantic Epilepsy and Sleep Center
RECRUITINGBathesda, Maryland, 20817, United States
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OnSite Clinical Solutions, LLC
RECRUITINGCharlotte, North Carolina, 28277, United States
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Quest Research Institute
RECRUITINGFarmington Hills, Michigan, 48334, United States
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