Which shoulder surgery works best for seniors with arthritis? a Head-to-Head trial

NCT ID NCT05395819

First seen Jul 09, 2026 · Last updated Jul 10, 2026 · Updated 1 time

Summary

This study compares two types of shoulder replacement surgery—Total Shoulder Arthroplasty (TSA) and Reverse Total Shoulder Arthroplasty (RTSA)—in people aged 65 and older with advanced shoulder osteoarthritis. Participants are randomly assigned to one of the two procedures. The goal is to see which surgery leads to better shoulder function, quality of life, and fewer complications within the first year after surgery. This pilot study will also help determine if a larger trial is feasible.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Reverse Total Shoulder Arthroplasty (RTSA) and Total Shoulder Arthroplasty (TSA) surgical procedures
What this could lead to
If one procedure proves clearly better, surgeons may have clearer guidance on which shoulder replacement to use for older patients with osteoarthritis, potentially improving outcomes and reducing complications.
What could go wrong
This is a small pilot study with only 40 participants, so results may not apply to everyone. The trial is early-stage and designed mainly to test feasibility, not to provide definitive answers.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Collaborative Orthopaedic Research (CORe), Clinical Sciences Building

    Edmonton, Alberta, T6G 2B7, Canada

  • Glen Sather Sports Medicine Clinic (University of Alberta)

    Edmonton, Alberta, T6G 1Z1, Canada

  • Grey Nuns Community Hospital

    Edmonton, Alberta, T6L 5X8, Canada

  • Kaye Edmonton Clinic

    Edmonton, Alberta, T6G 1Z1, Canada

  • Royal Alexandra Hospital (Orthopaedic Surgical Centre)

    Edmonton, Alberta, T5H 3V9, Canada

  • Sturgeon Community Hospital

    St. Albert, Alberta, T8N 6C4, Canada

  • University of Alberta Hospital

    Edmonton, Alberta, T6G 2B7, Canada

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