Could a common diabetes drug help drain dangerous belly fluid?
NCT ID NCT05999773
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study looks at whether SGLT2 inhibitors, a type of diabetes medication, can help control ascites (fluid buildup in the belly) in people with liver cirrhosis and type 2 diabetes. Researchers will compare 40 patients who add the drug to their usual treatment against those who stick with standard care alone. The goal is to see if the drug improves fluid control and blood sugar levels without causing serious side effects.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
SGLT2 inhibitors (a class of diabetes drugs)
What this could lead to
If it works, this could point toward a new way to manage ascites (fluid buildup) in people with liver cirrhosis and diabetes, potentially reducing the need for stronger diuretics.
What could go wrong
This is a small observational study (40 people) with no blinding or randomization, so results may not be reliable. SGLT2 inhibitors can cause side effects like urinary infections, dehydration, or kidney issues, especially in people with liver problems.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Department of Internal Medicine, University Hospital of Palermo
Palermo, Palermo, 90127, Italy
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Internal Medicine Unit, V. Cervello Hospital
Palermo, Italy, 90100, Italy