Could a simple blood test reveal hidden immune failure in septic shock?

NCT ID NCT04067674

First seen Jul 13, 2026 · Last updated Jul 14, 2026 · Updated 1 time

Summary

This study investigates why some patients with septic shock develop a weakened immune system after the initial crisis, making them prone to further infections. Researchers will analyze blood samples from 305 intensive care unit patients to find biological markers that indicate immune suppression. They will also test in the lab whether certain drugs can restore immune function. The goal is to better identify patients who could benefit from immune-boosting treatments.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to
If successful, this could help doctors identify which septic shock patients are most immunosuppressed and might benefit from immune-boosting therapies.
What could go wrong
This is an observational study focused on measuring biomarkers, not testing treatments directly. The findings may not lead to immediate clinical changes.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Hôpital Edouard Herriot

    RECRUITING

    Lyon, 69003, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

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