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Tiny study tests new therapy for stubborn depression

NCT ID NCT06655623

Completed Knowledge-focused Sponsor: Region of Southern Denmark Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looked at whether schema therapy, a type of talk therapy, could help people with depression that hasn't gotten better with usual treatments. Two participants received 30 therapy sessions over about a year. The goal was to see if this approach is feasible and to learn how to adapt it for this group.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
schema therapy
What this could lead to
If successful, this could point toward a new therapy option for people with depression that hasn't responded to standard treatments.
What could go wrong
This is a very small study with only 2 participants, so results may not apply to everyone. It's early research, not a proven treatment.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Depression depressive disorder Depressive Disorder, Treatment-Resistant dysthymic disorder major depressive disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CHRONIC DEPRESSION DEPRESSION MAJOR DEPRESSIVE DISORDER TREATMENT RESISTANT DEPRESSION

Contacts and locations

Locations

  • Psychotherapeutic Clinic Frederiksberg, Psychiatric Center Copenhagen, Mental Health Services, Capital Region of Denmark

    Frederiksberg, Denmark

  • Psychotherapeutic Out-patient Clinic, Psychiatric Center Copenhagen/Nannasgade, Mental Health Services, Capital Region of Denmark

    Copenhagen, 2200, Denmark

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