Zapping cancer spots: could radiation delay the need for stronger drugs?

This phase 2 trial tests whether giving focused radiation (SBRT) to a few growing prostate cancer spots, while staying on current therapy, can control the cancer better than switching to a new systemic therapy. About 75 men with castration-resistant prostate cancer that has a limited number of progressing lesions will be randomly assigned to either SBRT plus their current therapy or standard care (changing therapy). The main goals are to see if this approach is feasible and if it leads to a greater drop in PSA levels.