Zapping cancer spots: could radiation delay the need for stronger drugs?
NCT ID NCT06927635
First seen Jun 26, 2026 · Last updated Jun 26, 2026 · Updated 1 time
Summary
This phase 2 trial tests whether giving focused radiation (SBRT) to a few growing prostate cancer spots, while staying on current therapy, can control the cancer better than switching to a new systemic therapy. About 75 men with castration-resistant prostate cancer that has a limited number of progressing lesions will be randomly assigned to either SBRT plus their current therapy or standard care (changing therapy). The main goals are to see if this approach is feasible and if it leads to a greater drop in PSA levels.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Stereotactic Body Radiation Therapy (SBRT)
What this could lead to
If successful, this could offer a way to delay switching to stronger systemic therapy by using targeted radiation to control progressing prostate cancer spots.
What could go wrong
This is a small, early-phase trial (75 people) testing feasibility, not yet proven to improve survival. Radiation may cause side effects, and not all patients may benefit.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Princess Margaret Cancer Center
RECRUITINGToronto, Ontario, M5G 2M9, Canada
Contact Phone: •••-•••-•••• Email: •••••@•••••