Blood test could spot sarcoma without a biopsy

NCT ID NCT06958107

Recruiting now Knowledge-focused Sponsor: Wake Forest University Health Sciences Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jul 24, 2026 · Updated 3 times

Summary

This study is testing whether a blood test can find tiny bits of tumor DNA in people with sarcoma, a rare cancer of bone or soft tissue. Researchers will take blood samples before, during, and after treatment to see how well the test works. The goal is to learn if this liquid biopsy can track cancer over time without needing repeated surgical biopsies.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If successful, this could lead to a simple blood test to monitor sarcoma, potentially reducing the need for repeated tissue biopsies.
What could go wrong: This is an early-stage observational study, not a treatment trial. The blood test may not be sensitive enough to detect all sarcomas, and results may not change patient care.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

bone sarcoma sarcoma soft tissue sarcoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

SARCOMA

Contacts and locations

Locations

Atrium Health Wake Forest Baptist Comprehensive Cancer Center
RECRUITING

Winston-Salem, North Carolina, 27103, United States
Levine Cancer Institute
RECRUITING

Charlotte, North Carolina, 28204, United States

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