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Can magnetic pulses quiet the ringing in your ears?

NCT ID NCT01407133

Symptom relief Sponsor: Hospices Civils de Lyon Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested whether repetitive transcranial magnetic stimulation (rTMS) can help people with chronic, severe tinnitus (ringing in the ears). Sixty-four adults received either real or fake rTMS at different intensities. The goal was to see if the treatment reduces tinnitus loudness and is safe, with follow-up lasting up to a year.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
repetitive transcranial magnetic stimulation (rTMS) device
What this could lead to
If it works, this could point toward a non-invasive treatment to reduce the loudness of chronic tinnitus.
What could go wrong
This is an early-phase trial with only 64 participants, so results may not apply to everyone. The effect may be small or temporary, and some people may not benefit.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Phase 1/2

Runs two stages together: safety and dose first, then whether the treatment works.

Participants

64 people

The number who actually took part.

Start date

May 2005

Finished

Sep 2009

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 75 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Men and women between the ages of 18 and 75 years old; * Adequate medical condition (ASA P1 or P2 in Physical Status Classification System); * Disabling tinnitus (STSS \> 8/16 or THQ \> 50%), with the following characteristics: continuous, subjective, non-pulsatile; unilateral (or bilateral with unilateral predominance), chronic (duration for at least one year), refractory for usual treatments taken for at least six months; * Naive regarding TMS; * Able to provide informed consent. Exclusion Criteria: * Objective tinnitus or tinnitus with treatable cause; * Presence of intracranial or intraocular ferromagnetic materiel or particles (with the exception of dental fillings and MRI-compatible stapedectomy prosthesis); * Cardiac pacemaker or other electronic implants (including cochlear implant); * Serious heart disease or other unstable major medical condition; * Personal history of central nervous system disorder, head injury, stroke or seizures (including childhood febrile seizures); * Familial history of epilepsy; * Concomitant medication with antidepressants and antipsychotics; * Possibility of pregnancy; * Known claustrophobia; * Others known contraindications to rTMS or brain MRI; * Refusal to be informed about the results of anatomical MRI

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Conditions

The condition(s) this trial relates to.

tinnitus

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Chronic tinnitus

Contacts and locations

Locations

  • Département d'ORL et de Chirurgie Cervico-Maxillo-Faciale, Hôpital Edouard Herriot

    Lyon, 69437, France

  • Service d'Audiologie et Explorations Orofaciales, Centre Hospitalier Lyon Sud

    Pierre-Bénite, 69495, France

  • Service d'Oto-Rhino-Laryngologie, Centre Hospitalier Lyon-Sud

    Pierre-Bénite, 69495, France

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