New taxane drug RP-001 enters human trials for Hard-to-Treat cancers

NCT ID NCT07504263

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This early-phase trial is testing a new chemotherapy drug called RP-001 in 66 adults with advanced solid tumors, including colorectal and pancreatic cancers. The main goals are to check safety, find the best dose, and see if the drug can shrink tumors. It is an open-label study, meaning everyone knows they are getting the experimental drug.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
RP-001 (a new type of taxane chemotherapy)
What this could lead to
If it works, this could provide a new chemotherapy option for people with advanced colorectal or pancreatic cancer that has stopped responding to other treatments.
What could go wrong
This is a very early, small trial (66 people) focused on safety and dosing. The drug may not shrink tumors or could cause serious side effects like other chemotherapies.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

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