Could a common cholesterol drug slow liver scarring?

NCT ID NCT05832229

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether rosuvastatin, a cholesterol-lowering drug, can safely slow or stop liver scarring (cirrhosis) compared to a placebo. About 256 adults with compensated cirrhosis will take the drug or placebo for 2 years. The main goal is to measure changes in liver stiffness, a sign of disease progression.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

alcoholic liver cirrhosis cirrhosis of liver Fibrosis hepatitis C induced liver cirrhosis metabolic dysfunction-associated steatotic liver disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Cleveland Clinic

    ACTIVE_NOT_RECRUITING

    Cleveland, Ohio, 44192, United States

  • Columbia University Iriving School of Medicine

    RECRUITING

    New York, New York, 10031, United States

    Contact Email: •••••@•••••

  • Duke Liver Center

    RECRUITING

    Durham, North Carolina, 27710, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Email: •••••@•••••

  • Keck Medical Center of USC

    RECRUITING

    Los Angeles, California, 90033, United States

    Contact Email: •••••@•••••

  • LAC + USC Medical Center

    RECRUITING

    Los Angeles, California, 90033, United States

    Contact Email: •••••@•••••

  • Mayo Clinic

    RECRUITING

    Rochester, Minnesota, 55901, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • New York Presbyterian/Weill Cornell

    RECRUITING

    New York, New York, 10021, United States

    Contact Email: •••••@•••••

  • UCSF Medical Center

    RECRUITING

    San Francisco, California, 94143, United States

    Contact Email: •••••@•••••

  • UCSF/Zuckerberg San Francisco General Hospital and Trauma Center

    RECRUITING

    San Francisco, California, 94110, United States

    Contact Email: •••••@•••••

  • University of California San Diego NAFLD Research Center

    RECRUITING

    La Jolla, California, 92035, United States

    Contact Email: •••••@•••••

  • University of Miami Health System

    RECRUITING

    Miami, Florida, 33122, United States

    Contact Email: •••••@•••••

  • University of Michigan

    RECRUITING

    Ann Arbor, Michigan, 48109, United States

    Contact Email: •••••@•••••

  • Virginia Commonwealth University

    RECRUITING

    Richmond, Virginia, 23298, United States

    Contact Email: •••••@•••••