Could a common cholesterol drug slow liver scarring?
NCT ID NCT05832229
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests whether rosuvastatin, a cholesterol-lowering drug, can safely slow or stop liver scarring (cirrhosis) compared to a placebo. About 256 adults with compensated cirrhosis will take the drug or placebo for 2 years. The main goal is to measure changes in liver stiffness, a sign of disease progression.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Cleveland Clinic
ACTIVE_NOT_RECRUITINGCleveland, Ohio, 44192, United States
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Columbia University Iriving School of Medicine
RECRUITINGNew York, New York, 10031, United States
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Duke Liver Center
RECRUITINGDurham, North Carolina, 27710, United States
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Keck Medical Center of USC
RECRUITINGLos Angeles, California, 90033, United States
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LAC + USC Medical Center
RECRUITINGLos Angeles, California, 90033, United States
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Mayo Clinic
RECRUITINGRochester, Minnesota, 55901, United States
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New York Presbyterian/Weill Cornell
RECRUITINGNew York, New York, 10021, United States
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UCSF Medical Center
RECRUITINGSan Francisco, California, 94143, United States
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UCSF/Zuckerberg San Francisco General Hospital and Trauma Center
RECRUITINGSan Francisco, California, 94110, United States
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University of California San Diego NAFLD Research Center
RECRUITINGLa Jolla, California, 92035, United States
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University of Miami Health System
RECRUITINGMiami, Florida, 33122, United States
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University of Michigan
RECRUITINGAnn Arbor, Michigan, 48109, United States
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Virginia Commonwealth University
RECRUITINGRichmond, Virginia, 23298, United States
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