Could the smell of roses prevent sudden death in epilepsy?

NCT ID NCT07116421

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This early-phase study tests whether breathing in rose scent can reduce the number of times people with epilepsy stop breathing during seizures. Forty adults admitted to a hospital epilepsy monitoring unit will have their brain activity and breathing tracked for 48 hours, with rose scent diffused into their room for the second 24 hours. The goal is to see if this simple, pleasant smell can lower the risk of Sudden Unexpected Death in Epilepsy (SUDEP).

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
2-phenylethanol (rose scent) delivered via essential oil diffuser
What this could lead to
If it works, this could point toward a simple, non-invasive way to reduce breathing problems during seizures and potentially lower the risk of sudden death in epilepsy.
What could go wrong
This is a very early, small trial with only 40 participants and no control group. The effect may be small or absent, and some people may find the scent unpleasant or irritating.

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Conditions

The condition(s) this trial relates to.

epilepsy Sudden Unexpected Death in Epilepsy

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Vanderbilt University Medical Center

    RECRUITING

    Nashville, Tennessee, 37232, United States

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