Diabetes may worsen pain after root canal retreatment, study suggests

NCT ID NCT07679880

First seen Jul 01, 2026 · Last updated Jul 01, 2026

Summary

This study looks at whether people with diabetes experience more pain after a second root canal treatment compared to those without diabetes. About 50 adults with a single-rooted tooth needing retreatment will take part. Pain levels and painkiller use will be tracked for a week after the procedure. The study also explores how blood sugar control and diabetes medications relate to pain.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

root canal retreatment

What this could lead to

If successful, this study could help dentists better manage pain after root canal retreatment in people with diabetes.

What could go wrong

This is a small, early-stage study with only 50 participants, so results may not apply to everyone. Pain is subjective and hard to measure precisely.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

diabetes mellitus periapical periodontitis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Erciyes University

    Kayseri, Kayseri, 38039, Turkey (Türkiye)