Diabetes may worsen pain after root canal retreatment, study suggests

NCT ID NCT07679880

Completed Symptom relief Sponsor: TC Erciyes University Source: ClinicalTrials.gov ↗

First seen Jul 01, 2026 · Last updated Jul 02, 2026 · Updated 1 time

Summary

This study looks at whether people with diabetes experience more pain after a second root canal treatment compared to those without diabetes. About 50 adults with a single-rooted tooth needing retreatment will take part. Pain levels and painkiller use will be tracked for a week after the procedure. The study also explores how blood sugar control and diabetes medications relate to pain.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: root canal retreatment
What this could lead to: If successful, this study could help dentists better manage pain after root canal retreatment in people with diabetes.
What could go wrong: This is a small, early-stage study with only 50 participants, so results may not apply to everyone. Pain is subjective and hard to measure precisely.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

diabetes mellitus periapical periodontitis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

APICAL PERIODONTITIS

Contacts and locations

Locations

Erciyes University

Kayseri, Kayseri, 38039, Turkey (Türkiye)

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