Laser vs. standard: which root canal cleaner works best?

NCT ID NCT07439614

Recruiting now Disease control Sponsor: State University of New York at Buffalo Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study compares two methods for disinfecting root canals in teeth with apical periodontitis (an infection at the tooth root). Fifty adults with infected molars will receive either a laser-based disinfection or a standard protocol. The goal is to see which method reduces bacteria more effectively, measured by rapid ATP testing and lab analysis.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Er,Cr:YSGG laser (2780 nm) with radial-firing tip
What this could lead to: If successful, this could point toward a more effective way to disinfect root canals, potentially improving outcomes for patients with apical periodontitis.
What could go wrong: This is a small, early-stage study (50 participants) comparing two methods. Results may not apply to all teeth or patients, and the laser method may not prove superior to standard care.

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Conditions

The condition(s) this trial relates to.

periapical periodontitis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

PERIAPICAL PERIODONTITIS

Contacts and locations

Locations

Advance Education in Endodontics Program
RECRUITING

Buffalo, New York, 14214, United States

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