Light-Activated therapy boosts root canal disinfection?

NCT ID NCT07666932

First seen Jun 27, 2026 · Last updated Jul 01, 2026 · Updated 1 time

Summary

This study tested whether adding photodynamic therapy (a light-activated treatment) to standard sodium hypochlorite irrigation better kills bacteria in root canals. 64 adults needing root canal treatment were randomly assigned to receive either sodium hypochlorite alone or with photodynamic therapy. Bacterial levels were measured before and after treatment to see which method reduced germs more.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Sodium hypochlorite and photodynamic therapy (photosensitizing agent plus light)

What this could lead to

If it works, this could point toward a more effective way to disinfect root canals, reducing infection and pain after treatment.

What could go wrong

This is a small, completed study with only 64 participants. Results may not apply to all patients or tooth types, and photodynamic therapy adds time and cost.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

dental pulp necrosis periapical periodontitis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • University of Jordan

    Amman, Jordan