Light-Activated therapy boosts root canal disinfection?

NCT ID NCT07666932

First seen Jun 27, 2026 · Last updated Jul 02, 2026 · Updated 2 times

Summary

This study tested whether adding photodynamic therapy (a light-activated treatment) to standard sodium hypochlorite irrigation better kills bacteria in root canals. 64 adults needing root canal treatment were randomly assigned to receive either sodium hypochlorite alone or with photodynamic therapy. Bacterial levels were measured before and after treatment to see which method reduced germs more.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Sodium hypochlorite and photodynamic therapy (photosensitizing agent plus light)
What this could lead to
If it works, this could point toward a more effective way to disinfect root canals, reducing infection and pain after treatment.
What could go wrong
This is a small, completed study with only 64 participants. Results may not apply to all patients or tooth types, and photodynamic therapy adds time and cost.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • University of Jordan

    Amman, Jordan

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