Scientists probe immune Cells' role in scleroderma blood vessel injury

NCT ID NCT02636127

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This completed study looked at how certain immune cells (T cells and NK cells) might damage blood vessels in people with systemic sclerosis, a rare autoimmune disease. Researchers analyzed blood samples from 30 participants to measure a protein called Fractalkine and study cell interactions. The goal was to better understand the disease process, not to test a new treatment.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to
If successful, this research could point toward new treatment targets for systemic sclerosis by clarifying how immune cells injure blood vessels.
What could go wrong
This is a small, observational study with only 30 participants, so findings may not apply to all patients. It does not test a treatment, so direct benefits are unlikely.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for SCLERODERMA, SYSTEMIC are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Assistance Publique Hopitaux de Marseille

    Marseille, 13354, France

More trials for these conditions

Other studies related to the condition(s) this trial covers.