Cancer drug shows promise against rare Skin-Fibrosis disease

NCT ID NCT00479934

First seen May 18, 2026 · Last updated May 23, 2026 · Updated 2 times

Summary

This study tested whether imatinib (Glivec), a drug used for certain cancers, can reduce severe skin hardening in people with scleroderma. 28 adults with advanced skin involvement received either imatinib or a placebo for 6 months. The main goal was to measure changes in skin thickness using a standard scoring system, along with safety and quality-of-life checks.

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Contacts and locations

Locations

  • Néphrologie et Médecine interne - CH de Valenciennes

    Valenciennes, 59322, France

  • Service de Dermatologie - CHG Libourne

    Libourne, 33500, France

  • Service de Dermatologie - CHG Périgueux

    Périgueux, 24000, France

  • Service de Dermatologie - CHU de Toulouse - Hopital Purpan

    Toulouse, 31059 Toulouse Cedex, France

  • Service de Dermatologie - service de médecine interne et vasculaire - hopital haut Lévêque - av.de magellan

    Pessac, 33604, France

  • Service de Dermatologie et services de médecine interne et vasculaire - Hôpital St André - CHU de Bordeaux

    Bordeaux, 33076, France

  • Service de Médecin interne - Hôpital central

    Nancy, 54035, France

  • Service de Médecine interne - CHU de Tours

    Tours, 37044, France

  • Service de Médecine interne - Hôpital Saint Louis

    Paris, 75475, France

  • Service de Rhumatologie - CHU de Strasbourg

    Strasbourg, 67098, France

  • Service de Rhumatologie, Hôpital Pellegrin-Tondu CHU de Bordeaux

    Bordeaux, 33076, France

  • Service de dermatologie - CHU de Limoges

    Limoges, 87042, France

Conditions

Explore the condition pages connected to this study.