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Cancer drug shows promise for rare skin disease

NCT ID NCT00479934

Completed Disease control Sponsor: University Hospital, Bordeaux Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested whether imatinib, a drug used for certain cancers, can reduce skin hardening in people with severe scleroderma. 28 adults received either imatinib or a placebo for 6 months. The main goal was to see if the drug improved skin thickness and quality of life.

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Conditions

The condition(s) this trial relates to.

diffuse scleroderma localized scleroderma systemic sclerosis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

SCLERODERMA, LOCALIZED SCLERODERMA, SYSTEMIC

Contacts and locations

Locations

  • Néphrologie et Médecine interne - CH de Valenciennes

    Valenciennes, 59322, France

  • Service de Dermatologie - CHG Libourne

    Libourne, 33500, France

  • Service de Dermatologie - CHG Périgueux

    Périgueux, 24000, France

  • Service de Dermatologie - CHU de Toulouse - Hopital Purpan

    Toulouse, 31059 Toulouse Cedex, France

  • Service de Dermatologie - service de médecine interne et vasculaire - hopital haut Lévêque - av.de magellan

    Pessac, 33604, France

  • Service de Dermatologie et services de médecine interne et vasculaire - Hôpital St André - CHU de Bordeaux

    Bordeaux, 33076, France

  • Service de Médecin interne - Hôpital central

    Nancy, 54035, France

  • Service de Médecine interne - CHU de Tours

    Tours, 37044, France

  • Service de Médecine interne - Hôpital Saint Louis

    Paris, 75475, France

  • Service de Rhumatologie - CHU de Strasbourg

    Strasbourg, 67098, France

  • Service de Rhumatologie, Hôpital Pellegrin-Tondu CHU de Bordeaux

    Bordeaux, 33076, France

  • Service de dermatologie - CHU de Limoges

    Limoges, 87042, France

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