Could CAR T-Cells beat tough scleroderma? new trial aims to find out

NCT ID NCT07493395

First seen Apr 07, 2026 · Last updated May 15, 2026 · Updated 5 times

Summary

This early trial tests a one-time CAR T-cell treatment for 6 adults with severe scleroderma that hasn't improved with standard drugs. The goal is to see if it can reduce skin thickening and other symptoms, and to check for side effects. Participants will get the cells by IV after a short chemotherapy, then be followed for 2 years.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • APHP Necker

    Paris, France

    Contact

    Contact Email: •••••@•••••

  • CHRU Lille

    Lille, France

    Contact Email: •••••@•••••

    Contact

  • Chu Rouen

    Rouen, France

    Contact Email: •••••@•••••

  • Montpellier University Hospital

    Montpellier, France

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

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