New hope for scleroderma patients: tofacitinib takes on skin thickening

NCT ID NCT07472166

First seen Apr 17, 2026 · Last updated May 15, 2026 · Updated 3 times

Summary

This study tested whether tofacitinib, a drug that calms the immune system, works better than methotrexate for reducing skin thickening in people with a severe form of scleroderma. 34 adults with early-stage diffuse scleroderma took part. The main goal was to measure changes in skin hardness over 24 weeks using a standard scoring system.

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Contacts and locations

Locations

  • Department of Rheumatology, Bangabandhu Sheikh Mujib Medical University (BSMMU)

    Dhaka, 1000, Bangladesh

Conditions

Explore the condition pages connected to this study.