Brain device shows lasting seizure control in Real-World study

NCT ID NCT02403843

Completed Disease control Sponsor: NeuroPace Source: ClinicalTrials.gov ↗

First seen May 09, 2026 · Last updated May 16, 2026 · Updated 1 time

Summary

This study followed 345 people with epilepsy who use the RNS System, a brain implant that detects and stops seizures. Over 5 years, researchers tracked safety and how well the device reduces disabling seizures in everyday life. The goal was to confirm the device works safely outside of initial clinical trials.

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Contacts and locations

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Locations

Austin Epilepsy Care Center

Austin, Texas, 78758, United States
Dartmouth-Hitchcock Medical Cente

Lebanon, New Hampshire, 03756, United States
Emory University

Atlanta, Georgia, 30322, United States
Indiana University

Indianapolis, Indiana, 46202, United States
Intermountain Healthcare Research

Salt Lake City, Utah, 84157, United States
Le Bonheur Children's Hospital

Memphis, Tennessee, 38105, United States
Massachusetts General Hospital

Boston, Massachusetts, 02114, United States
NYU Langone Medical Center

New York, New York, 10016, United States
Norton Neuroscience Institute

Louisville, Kentucky, 40241, United States
Pennsylvania State University / Milton S. Hershey Medical Center

Hershey, Pennsylvania, 17033, United States
Rush University Medical Center

Chicago, Illinois, 60612, United States
Seton Family of Hospital

Austin, Texas, 78701, United States
Spectrum Health

Grand Rapids, Michigan, 49503, United States
Stanford University

Palo Alto, California, 94304, United States
Swedish Health Services

Seattle, Washington, 98122, United States
The Cleveland Clinic Foundation

Cleveland, Ohio, 44193, United States
The University of Texas Health Science Center at Houston

Houston, Texas, United States
Thomas Jefferson University

Philadelphia, Pennsylvania, 19107, United States
University of Alabama, Birmingham

Birmingham, Alabama, 35294, United States
University of California, Irvine

Irvine, California, 92868, United States
University of California, Los Angeles

Los Angeles, California, 90095, United States
University of California, San Francisco

San Francisco, California, 94143, United States
University of Colorado Denver

Aurora, Colorado, 80045, United States
University of Kentucky

Lexington, Kentucky, 40506, United States
University of Nebraska Medical Center

Omaha, Nebraska, 68198, United States
University of North Carolina at Chapel Hill

Chapel Hill, North Carolina, 27514, United States
University of Pennsylvania

Philadelphia, Pennsylvania, 19104, United States
University of South Florida

Tampa, Florida, United States
University of Southern California

Los Angeles, California, 90032, United States
University of Texas Southwestern Medical Center

Dallas, Texas, 75390-9036, United States
University of Utah

Salt Lake City, Utah, 84132-5901, United States
University of Washington Harborview Medical Center

Seattle, Washington, 98104, United States
University of Wisconsin-Madison

Madison, Wisconsin, 53705, United States
Vanderbilt University

Nashville, Tennessee, 37232, United States
Yale University

New Haven, Connecticut, 06520, United States

Conditions

Explore the condition pages connected to this study.

EPILEPSY