Growth factor plug aims to heal stubborn anal fistulas

NCT ID NCT06632418

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether a collagen plug soaked with a lab-made growth factor (rhPDGF-BB) can safely help heal complex anal fistulas—abnormal tunnels between the rectum and skin. The plug is implanted during a procedure, and the growth factor is meant to boost tissue repair. The trial includes 12 adults with a single fistula tract that has a draining seton in place, and will check for safety and healing at 3 months.

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Conditions

The condition(s) this trial relates to.

anal fistula Osteogenesis Imperfecta, Type IV

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Vanderbilt University Medical Center

    Nashville, Tennessee, 37203, United States