Which reversal drug causes fewer bathroom problems after surgery?

NCT ID NCT06948409

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This study reviewed records of 70,000 adults who had non-urinary surgery under general anesthesia. It compared two drugs used to reverse muscle relaxants: sugammadex and neostigmine (given with atropine or glycopyrrolate). The goal was to see which drug is linked to fewer cases of postoperative urinary retention, which can delay discharge from the recovery room. The study also looked at costs and unplanned hospital visits.

What this could mean

Our plain-language read of the trial. This is informational only โ€” not medical advice or a prediction.

Active substance
sugammadex or neostigmine (with atropine or glycopyrrolate)
What this could lead to
If this study finds one reversal drug causes less urinary retention, it could help doctors choose the safer option for patients after surgery.
What could go wrong
This is a retrospective study, meaning it looks back at past records, so it cannot prove cause and effect. Other factors could influence the results.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for ANESTHESIA are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

COFS syndrome Urinary Retention

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Beth Israel Deaconess Medical Center

    Boston, Massachusetts, 02215, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.