Muscle mass on CT scans may guide safer anesthesia dosing
NCT ID NCT06740877
First seen Aug 21, 2026 ยท Last updated Aug 21, 2026
Summary
This study looks at whether the amount of muscle a person has, measured from a routine CT scan, can predict how much of a muscle relaxant drug they need during surgery. Researchers will measure muscle mass in about 90 adults scheduled for colon surgery and compare it to the dose of rocuronium required to maintain deep muscle relaxation. The goal is to see if a simple imaging measurement could help doctors tailor anesthesia dosing to each patient.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- rocuronium (a neuromuscular blocking agent used during general anesthesia)
- What this could lead to
- If muscle mass from CT scans predicts drug needs, doctors could personalize anesthesia dosing, improving safety and recovery.
- What could go wrong
- This is a small observational study, so results may not apply broadly. The link between muscle mass and drug dose might be weak or influenced by other factors.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
-
90 people
The number who actually took part.
- Started
-
May 2025
- Finished
-
Jun 2026
- Lead sponsor
-
Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Patients scheduled for elective colon surgery under general anesthesia
- Ages
-
19 to 85 years
- Sex
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Anyone
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Those who voluntarily agreed and signed the written consent form before participating in the study * American Society of Anesthesiologists physical class (ASA class) 1-3 * Patients scheduled for elective colon surgery under general anesthesia * Patients undergoing abdominal computed tomography for routine preoperative preparation Exclusion Criteria: * Pregnant women * Decreased renal function (GFR\<60mL/min/1.73m2). * Patients taking drugs that affect deep neuromuscular blockade * Patients with a history of neuromuscular and muscle disorders
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Seoul National University Bundang Hospital
Seongnam-si, Gyeonggi-do, 13620, South Korea
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