Weekly shot could ease back pain and help weight loss in large trial

NCT ID NCT07035093

Ongoing Symptom relief Sponsor: Eli Lilly and Company Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jul 24, 2026 · Updated 2 times

Summary

This study tests a once-weekly injection called retatrutide to see if it can reduce chronic low back pain and help with weight loss in people who have obesity or overweight. About 586 participants will receive either the drug or a placebo for up to 80 weeks. The goal is to find a new treatment option for those whose back pain is linked to excess weight.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

Obesity obesity disorder Overweight

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CHRONIC LOW BACK PAIN (CLBP) OBESITY OVERWEIGHT

Contacts and locations

Show contact details

Locations

Aggarwal and Associates Limited

Brampton, L6T 0G1, Canada
Alpine Clinical Research Center

Boulder, Colorado, 80301, United States
Altoona Center For Clinical Research

Duncansville, Pennsylvania, 16635, United States
Ark Clinical Research - Fountain Valley

Fountain Valley, California, 92708, United States
Artemis Institute for Clinical Research

San Diego, California, 92123, United States
Bluewater Clinical Research Group Inc.

Sarnia, N7T 4X3, Canada
CIPREC

Buenos Aires, C1061AAS, Argentina
Care Access - Cape Breton

Sydney, B1M 0A1, Canada
Care Access - Lake Charles (Bayou Pines)

Lake Charles, Louisiana, 70601, United States
Care Access - Tampa

Tampa, Florida, 33625, United States
Center for Clinical Research

Winston-Salem, North Carolina, 27103, United States
Centro Medico Dra. Laura Maffei- Investigacion Clinica Aplicada

Buenos Aires, C1425AGC, Argentina
Centro Médico Viamonte

Buenos Aires, C1120AAC, Argentina
Centro Rosarino de Investigaciones Clinicas (CRICs)

Rosario, 2000, Argentina
Centro de Diagnóstico y Rehabilitación (CEDIR)

Santa Fe, 3000, Argentina
Centro de Investigaciones Clínicas Baigorria

Granadero Baigorria, 2152, Argentina
Charter Research - Lady Lake

The Villages, Florida, 32162, United States
Clinical Research Institute

Los Angeles, California, 90048, United States
Clinvest Headlands Llc

Springfield, Missouri, 65807, United States
Conquest Research

Winter Park, Florida, 32789, United States
Cotton O'Neil Clinical Research Center

Topeka, Kansas, 66606, United States
Dr. Anil K. Gupta Medicine Professional Corporation

Toronto, M9V 4B4, Canada
Flourish Research - Miami, LLC

Miami, Florida, 33135, United States
Fundación Respirar

Buenos Aires, C1426ABP, Argentina
FutureSearch Trials of Neurology

Austin, Texas, 78731, United States
Great Lakes Research Group, Inc.

Bay City, Michigan, 48706, United States
Houston Research Institute

Houston, Texas, 77079, United States
IMA Clinical Research St. Petersburg

St. Petersburg, Florida, 33704, United States
Instituto Médico Catamarca IMEC

Rosario, 2000, Argentina
Investigaciones Medicas Imoba Srl

Buenos Aires, C1056ABH, Argentina
K2 Medical Research - Daytona Beach

Daytona Beach, Florida, 32114, United States
MD First Research - Chandler

Chandler, Arizona, 85286, United States
MedVadis Research Corporation

Waltham, Massachusetts, 02451, United States
Mercy Family Clinic

Dallas, Texas, 75208, United States
New Phase Research and Development

Knoxville, Tennessee, 37909, United States
Podlaskie Centrum Psychogeriatrii

Bialystok, 15-756, Poland
Sovah Clinical Research-River District

Danville, Virginia, 24541, United States
St Joseph Heritage Healthcare

Fullerton, California, 92835, United States
Tucson Orthopaedic Institute - North Wyatt Drive

Tucson, Arizona, 85712, United States
Winterberry Research Inc.

Hamilton, L8J 0B6, Canada

More trials for these conditions

Other studies related to the condition(s) this trial covers.