New breathing therapy aims to cut ventilator dependence in ICU patients

NCT ID NCT06499389

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether early, intensive respiratory physiotherapy can improve cough strength in ICU patients with muscle weakness who are struggling to come off a ventilator. Fifty adults on breathing machines will receive either three daily sessions of specialized breathing exercises or standard care. The goal is to see if the extra therapy helps them breathe on their own more successfully.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

respiratory physiotherapy (intensive, instrumental, early)

What this could lead to

If successful, this approach could help ICU patients with muscle weakness breathe on their own sooner and reduce the risk of needing a breathing tube again.

What could go wrong

This is a small, early-stage trial with only 50 participants, so results may not apply to all patients. The intensive therapy may be tiring or uncomfortable for some.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for VENTILATOR WEANING are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

critical illness polyneuropathy

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Département d'Anesthésie Réanimation - Médecine Intensive, Centre Hospitalier Lyon Sud

    RECRUITING

    Lyon, 69495, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Médecine Intensive - Réanimation, Hôpital de la Croix Rousse

    RECRUITING

    Lyon, 69004, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Service d'Anesthésie et Réanimation, Hôpital de la Croix Rousse, GHN

    NOT_YET_RECRUITING

    Lyon, France, 69004, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••