New breathing therapy aims to cut ventilator dependence in ICU patients

NCT ID NCT06499389

Recruiting now Symptom relief Sponsor: Hospices Civils de Lyon Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether early, intensive respiratory physiotherapy can improve cough strength in ICU patients with muscle weakness who are struggling to come off a ventilator. Fifty adults on breathing machines will receive either three daily sessions of specialized breathing exercises or standard care. The goal is to see if the extra therapy helps them breathe on their own more successfully.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: respiratory physiotherapy (intensive, instrumental, early)
What this could lead to: If successful, this approach could help ICU patients with muscle weakness breathe on their own sooner and reduce the risk of needing a breathing tube again.
What could go wrong: This is a small, early-stage trial with only 50 participants, so results may not apply to all patients. The intensive therapy may be tiring or uncomfortable for some.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

critical illness polyneuropathy

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

VENTILATOR WEANING

Contacts and locations

Locations

Département d'Anesthésie Réanimation - Médecine Intensive, Centre Hospitalier Lyon Sud
RECRUITING

Lyon, 69495, France
Médecine Intensive - Réanimation, Hôpital de la Croix Rousse
RECRUITING

Lyon, 69004, France
Service d'Anesthésie et Réanimation, Hôpital de la Croix Rousse, GHN
NOT_YET_RECRUITING

Lyon, France, 69004, France

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