New weaning protocol offers hope for Ventilator-Dependent patients

NCT ID NCT06642714

Completed Disease control Sponsor: Capital Medical University Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested a structured weaning protocol for 250 tracheostomy patients who needed a ventilator for more than 21 days. The protocol gradually reduced ventilator support and used noninvasive ventilation and high-flow oxygen through the tracheostomy tube. The goal was to help patients breathe on their own for at least 5 days within 60 days. The results could lead to a safer, more effective way to wean patients off long-term ventilation.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Standardized stepwise weaning protocol (noninvasive ventilation and high-flow oxygen therapy)
What this could lead to: If successful, this protocol could help more tracheostomy patients safely come off ventilators, reducing complications and improving recovery.
What could go wrong: This was a single-arm study without a comparison group, so results may not apply to all patients. The protocol requires specialized care, and some patients may not tolerate the weaning process.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

PROLONGED MECHANICAL VENTILATION TRACHEOSTOMY VENTILATOR WEANING

Contacts and locations

Locations

Beijing Rehabilitation Hospital of Capital Medical University

Beijing, China

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