Kidney nerve zapping shows promise for tough blood pressure in kidney disease

NCT ID NCT04264403

First seen May 13, 2026 · Last updated May 14, 2026 · Updated 1 time

Summary

This study tested a procedure called renal denervation, which uses energy to calm overactive nerves in the kidneys, to see if it can lower blood pressure in people with chronic kidney disease (stage 3) whose blood pressure remains high despite taking 1-5 medications. 44 participants were randomly assigned to receive either the real procedure or a sham (fake) procedure. The main goal was to measure changes in 24-hour blood pressure over 12 months. This is a disease control approach, not a cure, as patients still need ongoing medication and monitoring.

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Contacts and locations

Locations

  • Clinical Research Center Nuremberg, Department of Nephrology, University Hospital Erlangen

    Nuremberg, Germany

  • Clinical Research Center, Department of Nephrology and Hypertension, University of Erlangen-Nuremberg

    Erlangen, 91054, Germany

  • Heinrich Heine University Düsseldorf, Nephrologie, Germany

    Düsseldorf, 40225, Germany

  • Klinik für Innere Medizin III, Kardiologie, Angiologie Und Internistische Intensivmedizin, Saarland University Hospital, Saarland University

    Homburg, 66421, Germany

Conditions

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