Zapping kidney nerves: a new hope for stubborn high blood pressure?
NCT ID NCT07742787
First seen Aug 03, 2026 · Last updated Aug 05, 2026 · Updated 2 times
Summary
This trial tests whether a procedure called renal denervation can safely lower blood pressure in people with chronic kidney disease (stage 3) whose hypertension is not controlled by medication. The procedure uses ultrasound energy to calm overactive nerves in the kidney that may contribute to high blood pressure. Half of the 20 participants will receive the real procedure, while the other half will undergo a sham (fake) procedure to compare effects. The main goal is to see if the treatment reduces average blood pressure over 24 hours.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- renal denervation using the Paradise® Ultrasound System
- What this could lead to
- If effective, this procedure could offer a new way to control blood pressure in people with chronic kidney disease, potentially reducing the need for multiple medications.
- What could go wrong
- This is a small, early-stage trial with only 20 participants, so results may not apply broadly. The procedure carries risks such as damage to the renal artery or changes in kidney function.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Hippocratio General Hospital
Athens, 11527, Greece
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