New drug aims to tame stubborn high blood pressure

NCT ID NCT07708441

First seen Jul 16, 2026 · Last updated Jul 17, 2026 · Updated 1 time

Summary

This study tests an experimental drug called HRS-1780 in people with uncontrolled or resistant hypertension—high blood pressure that stays high despite treatment. The trial compares three different doses of HRS-1780 against a placebo to see if it safely lowers blood pressure. Participants must have high blood pressure readings at the start and be on stable background therapy.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
an experimental drug called HRS-1780
What this could lead to
If successful, HRS-1780 could offer a new treatment option for people whose high blood pressure is not controlled by current medications.
What could go wrong
This is an early-to-mid-stage trial, so the drug may not prove effective or could have unexpected side effects. Results may not apply to all patients.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Army Characteristic Medical Center of the People's Liberation Army

    Chongqing, Chongqing Municipality, 400042, China

    Contact

  • Zhongshan Hospital, Fudan University

    Shanghai, Shanghai Municipality, 200080, China

    Contact

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