Brain training for spinal pain: new study tests reflex retraining

NCT ID NCT05492188

First seen Nov 01, 2025 · Last updated Jun 22, 2026 · Updated 35 times

Summary

This study tests whether training people to change a spinal reflex can reduce neuropathic pain after spinal cord injury. Fifteen participants will undergo about 50 sessions over 6.5 months. The goal is to see if this behavioral approach can lower pain and improve sensation.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Medical University of South Carolina

    RECRUITING

    Charleston, South Carolina, 29425, United States

    Contact Phone: •••-•••-••••

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Operant conditioning of cutaneous reflexes (behavioral training)

What this could lead to

If it works, this could offer a non-drug way to reduce chronic pain after spinal cord injury.

What could go wrong

This is a very small early study (15 people) with no control group, so results may not apply widely. The training requires 50 visits over 6.5 months, which is demanding.

Conditions

The condition(s) this trial relates to.

nervous system injury neuralgia Pain spinal cord injury

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.