New drug duo aims to wipe out rectal tumors before surgery

NCT ID NCT04503694

Summary

This trial is testing whether adding two drugs, regorafenib and nivolumab, to standard short-course radiation can better shrink rectal tumors before surgery. The goal is to see if this combination leads to a complete disappearance of the tumor, potentially allowing some patients to avoid surgery. It involves 72 adults with stage 2 or 3 rectal cancer who are eligible for curative treatment.

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Contacts and locations

Locations

  • AZ Groeninge

    Kortrijk, 8500, Belgium

  • CHR Namur

    Namur, 5000, Belgium

  • CHU Ambroise Paré

    Mons, 7000, Belgium

  • Chirec Delta

    Brussels, 1160, Belgium

  • Cliniques Universitaires Saint-Luc

    Brussels, 1200, Belgium

  • Grand Hopital de Charleroi

    Gilly, 6060, Belgium

  • Institut Jules Bordet

    Anderlecht, 1070, Belgium

  • UZ Gent

    Ghent, 9000, Belgium

  • UZAntwerpen

    Edegem, 2650, Belgium

Conditions

Explore the condition pages connected to this study.