Brain bleed survivors: does clot removal protect your memory years later?

NCT ID NCT05611918

First seen Jun 24, 2026 · Last updated Jun 24, 2026

Summary

This study follows 350 people who survived a brain bleed (intracerebral hemorrhage) and were part of earlier trials testing clot-removal surgery. Researchers will test memory, thinking, and movement over time using phone interviews and blood samples. The goal is to see if removing the clot reduces long-term cognitive decline and signs of ongoing brain inflammation.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Albert Einstein Montefiore

    The Bronx, New York, 10461, United States

  • CommonSpirit (formerly Mercy San Juan Medical Center; dignity health)

    Chicago, Illinois, 60606, United States

  • Dignity Health component - St. Joseph's Hospital and Medical Center

    Sacramento, California, 95819, United States

  • Hennepin Healthcare Research Institute

    Minneapolis, Minnesota, 55415, United States

  • Henry Ford Health System

    Detroit, Michigan, 48202, United States

  • Inova Health System Foundation

    Fairfax, Virginia, 22042, United States

  • Johns Hopkins Hospital

    Baltimore, Maryland, 21205, United States

  • Mayo Clinic, Jacksonville

    Jacksonville, Florida, 32224, United States

  • Rutgers - Robert Wood Johnson Medical School

    Piscataway, New Jersey, 08854, United States

  • Scripps Health

    La Jolla, California, 92037, United States

  • Stanford University

    Stanford, California, 94305, United States

  • Thomas Jefferson University

    Philadelphia, Pennsylvania, 19107, United States

  • University of Alabama at Brimingham

    Birmingham, Alabama, 35294, United States

  • University of Cincinnati

    Cincinnati, Ohio, 45220, United States

  • University of Illinois at Chicago

    Chicago, Illinois, 60607, United States

  • University of Kansas Medical Center

    Fairway, Kansas, 66205, United States

  • University of Louisville

    Louisville, Kentucky, 40292, United States

  • University of Maryland Baltimore

    Baltimore, Maryland, 21201, United States

  • University of Michigan

    Ann Arbor, Michigan, 48109, United States

  • University of New Mexico

    Albuquerque, New Mexico, 87131, United States

  • University of Texas Health Science Center at San Antonio

    San Antonio, Texas, 78229, United States

  • University of Texas, Houston Health Science Center

    Houston, Texas, 77030, United States

  • Vanderbilt University Medical Center

    Nashville, Tennessee, 37232, United States

  • Wake Forest University Health Sciences

    Winston-Salem, North Carolina, 27157, United States

  • Washington University in St. Louis, School of Medicine

    St Louis, Missouri, 63130, United States

  • Yale University

    New Haven, Connecticut, 06511, United States

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to

If successful, this could show that early surgical clot removal helps prevent long-term memory and thinking problems after a brain bleed.

What could go wrong

This is an observational follow-up study, not a new treatment trial. It cannot prove cause and effect, and results may not apply to all stroke survivors.

Conditions

The condition(s) this trial relates to.

Cognitive Dysfunction Hemorrhage hemorrhage, intracerebral, susceptibility to intracerebral hemorrhage intracranial thrombosis Memory Disorders Motor Activity stroke disorder thrombotic disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.