MEMORY IMPAIRMENT

This study tests a home-based program called HOBSCOTCH-CA to help brain cancer survivors improve their memory, thinking, and quality of life. About 125 participants (including veterans and civilians) will either start the program right away or wait 3 months. The program involves …

This study tests whether 6 months of supervised aerobic exercise (like walking or cycling) can boost fitness, reduce brain damage, and improve memory in adults 65 and older with mild cognitive impairment or early Alzheimer's. Participants will exercise regularly, have memory test…

This study tests a new program that helps people aged 50 and older remember and use sleep-improving strategies. Participants have sleep or body-clock problems and mild memory issues. The goal is to see if better memory for treatment leads to better sleep, daily function, and life…

This study tests a home-based program called HOBSCOTCH-MS for people with multiple sclerosis who have memory or thinking problems. Participants meet weekly with a coach online to learn problem-solving and relaxation skills. The goal is to see if the program improves quality of li…

This study tests two types of talk therapy—cognitive behavioral therapy (CBT) and mindfulness-based therapy—to see which works better for treating insomnia and related depression in people who have had a mild to moderate traumatic brain injury (TBI) and also have post-traumatic s…

This study tests whether breathing air with slightly less oxygen (intermittent hypoxia training) can safely improve memory and thinking in people aged 55-79 with mild cognitive impairment. Over 12 weeks, participants will be randomly assigned to receive the treatment or a sham (f…

This study is testing a safe, home-based brain stimulation technique called RS-tDCS+ combined with cognitive training to improve attention in 160 active-duty service members and veterans who have had a mild traumatic brain injury. Participants will receive either real or sham sti…

This study is gathering data from 1,200 older adults (ages 60-90) who are either cognitively normal, have mild memory problems, or have mild-to-moderate Alzheimer's. Researchers will compare digital tests (like smartphone tasks) and blood markers with brain scans to see if these …

This study looks at how getting older and feeling stressed can change the way we remember and find our way around. Researchers will have 85 adults aged 65-80 do a virtual navigation task while their brains are scanned. Some will be put under mild stress to see if it makes them re…