Could umbilical cord stem cells save lungs in ARDS?
NCT ID NCT03042143
First seen Jun 26, 2026 · Last updated Jun 26, 2026
Summary
This trial tests whether a single infusion of stem cells from donated umbilical cords can help people with acute respiratory distress syndrome (ARDS), a severe lung condition often seen in intensive care. The study first finds a safe dose, then randomly gives either stem cells or a placebo to 129 patients on ventilators. Researchers will measure lung function and side effects to see if the treatment is promising.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
umbilical cord stem cells
What this could lead to
If it works, this could point toward a new treatment for ARDS, a life-threatening lung condition with few effective options.
What could go wrong
This is an early-phase trial (Phase 1/2) with a small number of participants. The stem cell treatment may not improve outcomes or could cause unexpected side effects.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Belfast Health and Social Care Trust, Royal Hospitals
Belfast, Northern Ireland, BT12 6BA, United Kingdom