Could a blood gel patch up anal fistulas without surgery?

NCT ID NCT05641844

Recruiting now Disease control Sponsor: RedDress Ltd. Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests a new treatment called RD2 Ver.02, a gel made from a patient's own blood, for healing anal fistulas. About 110 adults with certain types of fistulas will receive either the gel or a saltwater placebo after the fistula is cleaned and stitched closed. The main goal is to see if the gel helps the fistula heal better and with fewer complications over 6 months, and if it stays healed after a year.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: RD2 Ver.02 (a gel made from the patient's own blood)
What this could lead to: If it works, this could offer a simple, non-surgical way to heal anal fistulas and reduce the chance of them coming back.
What could go wrong: This is an early-stage trial with only 110 people, so results may not apply to everyone. The treatment might not heal the fistula or could cause infection.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

anal fistula

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ANAL FISTULA

Contacts and locations

Locations

Allegheny Health Network
RECRUITING

Pittsburgh, Pennsylvania, 15212, United States
Brown surgical associates
RECRUITING

Providence, Rhode Island, 02904, United States
Cleveland Clinic
RECRUITING

Weston, Florida, 33331, United States
Franciscan Health
RECRUITING

Indianapolis, Indiana, 46237, United States
Karen Zaghiyan, M.D
COMPLETED

Los Angeles, California, 90048, United States
Lenox Hill Hospital
RECRUITING

New York, New York, 10075, United States
Mayo Clinic
RECRUITING

Rochester, Minnesota, 55905, United States
Sheba Medical Center
RECRUITING

Ramat Gan, Israel
UMASS
RECRUITING

Worcester, Massachusetts, 01605, United States
University of Chicago
RECRUITING

Chicago, Illinois, 60637, United States

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