Could a blood gel patch up anal fistulas without surgery?
NCT ID NCT05641844
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests a new treatment called RD2 Ver.02, a gel made from a patient's own blood, for healing anal fistulas. About 110 adults with certain types of fistulas will receive either the gel or a saltwater placebo after the fistula is cleaned and stitched closed. The main goal is to see if the gel helps the fistula heal better and with fewer complications over 6 months, and if it stays healed after a year.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
RD2 Ver.02 (a gel made from the patient's own blood)
What this could lead to
If it works, this could offer a simple, non-surgical way to heal anal fistulas and reduce the chance of them coming back.
What could go wrong
This is an early-stage trial with only 110 people, so results may not apply to everyone. The treatment might not heal the fistula or could cause infection.
Disclaimer
Read more
Show less
This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for ANAL FISTULA are added.
By submitting, you agree to our Terms of use
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Show contact details
Enter your email to view the contact information for this study.
By submitting, you agree to our Terms of use
Study contacts
-
Contact
Phone: •••-•••-•••• Email: •••••@•••••
-
Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
-
Allegheny Health Network
RECRUITINGPittsburgh, Pennsylvania, 15212, United States
Contact Email: •••••@•••••
-
Brown surgical associates
RECRUITINGProvidence, Rhode Island, 02904, United States
Contact Email: •••••@•••••
-
Cleveland Clinic
RECRUITINGWeston, Florida, 33331, United States
Contact Email: •••••@•••••
Contact
-
Franciscan Health
RECRUITINGIndianapolis, Indiana, 46237, United States
Contact
-
Karen Zaghiyan, M.D
COMPLETEDLos Angeles, California, 90048, United States
-
Lenox Hill Hospital
RECRUITINGNew York, New York, 10075, United States
Contact Email: •••••@•••••
-
Mayo Clinic
RECRUITINGRochester, Minnesota, 55905, United States
Contact Email: •••••@•••••
-
Sheba Medical Center
RECRUITINGRamat Gan, Israel
Contact
-
UMASS
RECRUITINGWorcester, Massachusetts, 01605, United States
Contact Email: •••••@•••••
-
University of Chicago
RECRUITINGChicago, Illinois, 60637, United States
Contact Email: •••••@•••••