Could a few days of radiation replace weeks for sarcoma patients?
NCT ID NCT05109494
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study compares a shorter, more intense course of radiation (5 sessions) to the standard longer course (25 sessions) given before surgery for soft tissue sarcoma. The goal is to see if the shorter schedule is safe and effective at killing tumor cells. Thirty adults with sarcoma in their arms, legs, trunk, or head/neck will take part and be followed for up to 5 years.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
radiation therapy (hypofractionated or conventionally fractionated)
What this could lead to
If successful, this could show that a shorter course of radiation before surgery is just as safe and effective as the standard longer course, making treatment more convenient.
What could go wrong
This is a small, early-phase trial with only 30 participants, so results may not apply to everyone. The shorter radiation schedule might not kill as much tumor tissue or could cause different side effects.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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University of Wisconsin Hospital and Clinics
RECRUITINGMadison, Wisconsin, 53705, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••