Cure My Disease

Don't miss your cure!

 Log in / Sign up

Dentists test two materials to save painful teeth without root canals

NCT ID NCT07483788

Symptom relief Sponsor: Dow University of Health Sciences Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests two materials, MTA and Biodentine, for treating a painful tooth condition called irreversible pulpitis. 60 adults with severe tooth pain will get a pulpotomy (removing infected pulp) and one of the materials. They will be followed for 3 months to see which material leads to better healing and less pain.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Mineral Trioxide Aggregate (MTA) and Biodentine
What this could lead to
If one material works better, dentists may have a clearer choice for saving painful teeth without root canals.
What could go wrong
This is a small, short-term study (60 people, 3 months). Results may not apply to all patients or last long-term.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 60 people

The number the study aims to enrol. It can still change while the study runs.

Started

Nov 2024

Expected to finish

Jul 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 40 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: Teeth of generally healthy patients having following criteria will be included: 1. Age between 18-40 years of both males and females 2. Carious exposed maxillary and mandibular molars teeth 3. Moderate to severe pain (VAS 4-10) 4. Diagnosed with Symptomatic irreversible pulpitis on cold test and Electric pulp test (EPT) 5. Periapical index of 1 6. Hemostasis is achieved within 10 mins after full pulpotomy Exclusion Criteria: Teeth of generally healthy patients having following criteria will be excluded: 1. Any traumatic injury 2. Non-restorable carious lesion 3. Immature or Open apices of roots 4. Internal or external Resorption 5. Calcified canals

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for Symptomatic irreversible pulpitis (SIP) are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

pulpitis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Symptomatic irreversible pulpitis (SIP)

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    2 sites. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Dr Khadija Zubair

    RECRUITING

    Karachi, Sindh, Pakistan

  • Dr Khadija Zubair

    RECRUITING

    Karachi, Sindh, Pakistan

More trials for these conditions

Other studies related to the condition(s) this trial covers.