Dentists test two materials to save painful teeth without root canals

NCT ID NCT07483788

Recruiting now Symptom relief Sponsor: Dow University of Health Sciences Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests two materials, MTA and Biodentine, for treating a painful tooth condition called irreversible pulpitis. 60 adults with severe tooth pain will get a pulpotomy (removing infected pulp) and one of the materials. They will be followed for 3 months to see which material leads to better healing and less pain.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Mineral Trioxide Aggregate (MTA) and Biodentine
What this could lead to: If one material works better, dentists may have a clearer choice for saving painful teeth without root canals.
What could go wrong: This is a small, short-term study (60 people, 3 months). Results may not apply to all patients or last long-term.

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Conditions

The condition(s) this trial relates to.

pulpitis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

SYMPTOMATIC IRREVERSIBLE PULPITIS (SIP)

Contacts and locations

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Study contacts

Contact

Phone: •••-•••-•••• Email: •••••@•••••

Locations

Dr Khadija Zubair
RECRUITING

Karachi, Sindh, Pakistan
Dr Khadija Zubair
RECRUITING

Karachi, Sindh, Pakistan

Contact

Contact

Contact Phone: •••-•••-•••• Email: •••••@•••••

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