Could five doses of proton therapy before surgery improve sarcoma outcomes?

NCT ID NCT05917301

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study is testing whether a shorter course of proton therapy (just five treatments) before surgery for soft tissue sarcoma is safe and effective. Researchers will track wound healing, side effects, and quality of life in 40 adult patients over two years. The goal is to see if this approach can speed up treatment while keeping outcomes good.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

proton therapy (hypofractionated)

What this could lead to

If successful, this could offer a faster, safer radiation option before sarcoma surgery, reducing treatment time and possibly improving recovery.

What could go wrong

This is a small, early-phase trial with only 40 participants, so results may not apply to all patients. There is a risk of wound complications or other side effects from the radiation.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

sarcoma soft tissue sarcoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Email: •••••@•••••

Locations

  • Sibley Memorial Hospital

    RECRUITING

    Washington D.C., District of Columbia, 20016, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••