Shorter, stronger radiation for prostate cancer shows promise in new trial
NCT ID NCT03987386
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This phase 3 trial tests whether a shorter, higher-dose radiation schedule (hypofractionated) works as well as the standard longer course for men with prostate cancer who have had surgery. About 186 men will be randomly assigned to one of the two radiation plans. The study tracks side effects, cancer control, and quality of life to see if the shorter approach is safer and just as effective.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Radiation therapy (hypofractionated vs. conventional)
- What this could lead to
- If successful, this could offer a more convenient, shorter course of radiation after prostate cancer surgery with fewer side effects.
- What could go wrong
- This is a mid-stage trial with 186 participants, so results may not apply to all patients. The higher-dose approach could also increase some side effects.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
M D Anderson Cancer Center
Houston, Texas, 77030, United States
-
MD Anderson League City
League City, Texas, 77573, United States
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MD Anderson in Sugar Land
Sugar Land, Texas, 77478, United States
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Can a three-drug cocktail outsmart resistant prostate cancer?
- Precision radiation may tame rising PSA after prostate surgery
- Hormone therapy plus precision radiation aims to crush prostate cancer early
- Double-Dose precision: new combo radiation aims to shrink prostate tumors faster
- New scan could spot hidden aggressive prostate cancer in men who think They're safe
- Freezing or heating prostate tumors: a targeted alternative to surgery?