Freezing or heating prostate tumors: a targeted alternative to surgery?

NCT ID NCT06178354

First seen Jun 30, 2026 · Last updated Jul 01, 2026 · Updated 1 time

Summary

This trial tests whether focal ablation—using extreme cold (cryotherapy) or high-intensity ultrasound (HIFU)—can effectively destroy prostate tumors while leaving healthy tissue unharmed. It enrolls men with early-stage, localized prostate cancer that shows up on MRI. The goal is to control the disease with fewer side effects than whole-gland treatments like surgery or radiation.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

focal cryotherapy or high-intensity focused ultrasound

What this could lead to

If successful, this approach could offer a less invasive treatment option for localized prostate cancer, potentially reducing side effects like incontinence and impotence compared to whole-gland treatments.

What could go wrong

This is a phase 2 study with only 100 participants, so results are preliminary. The cancer may not be fully controlled, and some men may still need additional treatment. Risks include infection, bleeding, and urinary or sexual problems.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

prostate cancer prostate carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • University of California Davis Comprehensive Cancer Center

    RECRUITING

    Sacramento, California, 95817, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••