New imaging agent could spot returning prostate cancer earlier

NCT ID NCT04838613

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This completed Phase 3 study tested a new radioactive tracer called [18F]CTT1057 for PET/CT scans in 190 men with prostate cancer whose PSA levels were rising after initial treatment. The goal was to see if the tracer could accurately locate where the cancer had returned. Participants received both the new tracer and a standard one for comparison.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

[18F]CTT1057 (a radioactive tracer for PET scans)

What this could lead to

If successful, this could provide a more accurate way to detect where prostate cancer has returned after initial treatment, helping guide further therapy.

What could go wrong

This is a diagnostic study, not a treatment. The tracer may not be more effective than existing options, and false positives or negatives are possible.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

prostate cancer prostate neoplasm Recurrence

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Explorer Molecular Imaging center

    Sacramento, California, 95816, United States

  • Novartis Investigative Site

    Marseille, 13273, France

  • Novartis Investigative Site

    Marseille, 13885, France

  • Novartis Investigative Site

    Nîmes, 30029, France

  • Novartis Investigative Site

    Pierre-Bénite, 69495, France

  • Novartis Investigative Site

    Saint-Priest-en-Jarez, 42270, France

  • Novartis Investigative Site

    Toulouse, 31059, France

  • Novartis Investigative Site

    L'Hospitalet de Llobregat, Barcelona, 08907, Spain

  • Novartis Investigative Site

    Barcelona, Catalonia, 08035, Spain

  • Novartis Investigative Site

    Barcelona, 08036, Spain

  • Novartis Investigative Site

    Barcelona, 08041, Spain

  • Novartis Investigative Site

    Valencia, 46026, Spain

  • Novartis Investigative Site

    Geneva, 1211, Switzerland