RECURRENCE

This trial tests whether applying a cold, non-thermal plasma (a kind of energized gas) to the surgical site during standard drainage of a chronic subdural hematoma (a slow brain bleed) can lower the chance it comes back. Forty adults needing surgery will be randomly assigned to g…

This phase 2 trial tests whether a single injection of DNX-2401, a virus designed to kill cancer cells, can shrink or stabilize recurrent high-grade brain tumors in 39 children and young adults. Participants receive the virus directly into the tumor during a biopsy procedure. The…

This study compares two types of drainage after surgery for chronic subdural hematoma (a blood collection on the brain). 354 adults in Denmark will receive either active drainage under the scalp or passive drainage under the brain's outer layer for 24 hours. The goal is to see wh…

This study is testing two new diagnostic kits that use blood samples or tumor tissue to predict if early-stage lung cancer will come back after surgery. Researchers will enroll 236 people with stage IA to IIIA lung cancer who have had their tumor fully removed. The goal is to see…

This study tests whether a specific body posture—raising the legs and tilting the head—can prevent chronic subdural hematoma from recurring after surgery. The trial will enroll 830 older adults who have had surgery for this type of brain bleed. Participants will be randomly assig…

This study is testing whether a new tool called xDRIVE, which combines artificial intelligence and tumor profiling, can quickly suggest personalized treatment options for cancer patients in Florida whose cancer has come back or not responded to standard treatments. The goal is to…

This study looks at whether a blood test that detects tiny bits of tumor DNA after surgery can help decide which stage II colon cancer patients should get chemotherapy. About 1,320 patients will be randomly assigned to either have their test results used to guide treatment or to …

This study looks at whether exercise after finishing cancer treatment is linked to better outcomes, like longer survival without the cancer coming back. Researchers will analyze data from 1,000 adult cancer survivors at Memorial Sloan Kettering. The goal is to see if those who ex…

This study looks at how well the Triathlon Hinge Knee System works in people who need knee replacement surgery, either for the first time or to fix a previous one. Researchers will follow about 200 patients for up to 10 years to see how long the implant lasts and how well patient…