New study aims to find safer anesthesia dosing for obese patients

NCT ID NCT05305313

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether dosing the anesthetic propofol based on adjusted body weight is better than total body weight for obese patients. Using a computer-controlled system, researchers will monitor brain activity to maintain the right depth of anesthesia. The goal is to avoid overdosing and improve recovery. Forty-six obese adults undergoing surgery will participate.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Propofol

What this could lead to

If successful, this could lead to safer, more precise anesthesia dosing for obese patients, reducing risks like overdose or delayed recovery.

What could go wrong

This is a small, early-phase study with only 46 participants, so results may not apply to all obese patients or surgeries. The closed-loop system may also have technical limitations.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

morbid obesity

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Nitin Sethi

    RECRUITING

    New Delhi, National Capital Territory of Delhi, 110060, India

    Contact

    Contact

    Contact

    Contact

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact