New study aims to find safer anesthesia dosing for obese patients

NCT ID NCT05305313

Recruiting now Knowledge-focused Sponsor: Sir Ganga Ram Hospital Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether dosing the anesthetic propofol based on adjusted body weight is better than total body weight for obese patients. Using a computer-controlled system, researchers will monitor brain activity to maintain the right depth of anesthesia. The goal is to avoid overdosing and improve recovery. Forty-six obese adults undergoing surgery will participate.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Propofol
What this could lead to: If successful, this could lead to safer, more precise anesthesia dosing for obese patients, reducing risks like overdose or delayed recovery.
What could go wrong: This is a small, early-phase study with only 46 participants, so results may not apply to all obese patients or surgeries. The closed-loop system may also have technical limitations.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

morbid obesity

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ANESTHESIA OBESITY, MORBID PROPOFOL

Contacts and locations

Locations

Nitin Sethi
RECRUITING

New Delhi, National Capital Territory of Delhi, 110060, India

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