Can probiotics soothe IBS in obesity? new study investigates

NCT ID NCT04760353

Completed Symptom relief Sponsor: University Hospital Rijeka Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested whether a daily probiotic powder could relieve irritable bowel syndrome (IBS) symptoms in 80 obese adults. Participants took either the probiotic or a placebo for 8 weeks. Researchers tracked symptom relief and changes in gut bacteria.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Probiotic mixture (OMNi-BiOTiC STRESS) containing 9 bacterial strains and B vitamins
What this could lead to: If it works, this could point toward a simple probiotic supplement to ease IBS symptoms in people with obesity.
What could go wrong: This is a small, completed trial with only 80 participants. The results may not apply to everyone, and probiotics don't work for all.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

irritable bowel syndrome Obesity obesity disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

IBS (IRRITABLE BOWEL SYNDROME) OBESITY

Contacts and locations

Locations

Clinical Hospital Centre

Rijeka, Croatia, 51000, Croatia
University Hospital Rijeka

Rijeka, Rijeka, 51000, Croatia

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